Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)

Description

Fragment 176-191 & CJC-1295 & Ipamorelin Peptide Blend — Long Description

The Fragment 176-191 & CJC-1295 & Ipamorelin Peptide Blend is a research peptide formulation that has attracted growing interest among scientists for its potential synergistic role in growth hormone (GH) modulation, fat metabolism, and body composition regulation. This blend combines three well-known peptides — CJC-1295, Ipamorelin, and Fragment 176-191 — each of which is thought to exert distinct yet complementary biological effects that may influence GH activity and metabolic processes.

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CJC-1295

CJC-1295 is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH), consisting of 29 amino acids. It appears to work by binding to and activating GHRH receptors in the pituitary gland, potentially stimulating the natural release of growth hormone. CJC-1295 also includes a Drug Affinity Complex (DAC) modification designed to extend its half-life and duration of action, allowing for sustained GH release over time. Research suggests that this peptide may support enhanced protein synthesis, improved recovery, and increased lean muscle mass.

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Ipamorelin

Ipamorelin is a synthetic pentapeptide classified as a Growth Hormone Secretagogue (GHS). It is believed to mimic the natural hunger hormone ghrelin by activating ghrelin receptors (GHS-R1a) in the pituitary gland, leading to a selective release of growth hormone without affecting cortisol or prolactin levels. Research indicates that Ipamorelin may play a role in stimulating GH secretion, improving muscle repair, enhancing bone density, and possibly aiding in metabolic balance.

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Fragment 176-191

Fragment 176-191, sometimes referred to as AOD 9604, is a small portion of the human growth hormone (hGH) molecule. Composed of 15 amino acids, this peptide fragment has been studied for its potential lipolytic (fat-burning) effects. It may act on beta-3 adrenergic receptors (ADRB3) to encourage fat metabolism and thermogenesis, particularly in adipose tissues. Researchers have suggested that Fragment 176-191 may aid in fat reduction and energy regulation, making it a valuable component in studies exploring metabolic optimization.

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Synergistic Potential

When combined, CJC-1295, Ipamorelin, and Fragment 176-191 may work synergistically to support enhanced growth hormone secretion, improved fat metabolism, and optimized lean muscle composition. CJC-1295 and Ipamorelin may elevate circulating GH and IGF-1 levels, while Fragment 176-191 may assist in promoting lipolysis and preventing lipogenesis. Collectively, this blend may contribute to a more balanced anabolic and metabolic environment in preclinical studies.

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Research Applications

This peptide blend is being studied for its potential roles in:

• Stimulating endogenous growth hormone release

• Supporting muscle growth and repair

• Promoting fat metabolism and weight regulation

• Enhancing sleep quality and recovery

• Supporting joint and cartilage regeneration

• Improving bone density and tissue recovery

While results from early-stage trials and animal studies appear promising, it’s important to note that this peptide blend is intended strictly for research and laboratory purposes.

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Chemical Information

• Fragment 176-191: C₇₈H₁₂₅N₂₃O₂₃S₂ | Molecular Weight: 1817.12 g/mol

• CJC-1295 (Mod GRF 1-29): C₁₅₂H₂₅₂N₄₄O₄₂ | Molecular Weight: 3367.9 g/mol

• Ipamorelin: C₃₈H₄₉N₉O₅ | Molecular Weight: 711.8 g/mol

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References

1. National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 91976842, CJC1295 Without DAC. NCBI Link

2. National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 9831659, Ipamorelin. NCBI Link

3. National Center for Biotechnology Information (2023). PubChem Substance Record for SID 319360420, Fragment 176-191. NCBI Link

4. Ionescu M, Frohman LA. Pulsatile Growth Hormone Secretion Persists During Continuous GHRH Stimulation.

5. Madalina Ionescu et al., Effects of Long-Acting GHRH Analogues on GH and IGF-I Levels in Humans.

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Important Note

Fragment 176-191 & CJC-1295 & Ipamorelin Peptide Blend is sold for laboratory research purposes only. It is not intended for human consumption, medical use, or diagnostic applications. Always review and comply with your institution’s research safety and handling protocols before ordering.